Can You Take Unisom While Pregnant?

Does taking Unisom while pregnant help with nausea and insomnia?

More importantly, is it safe?

Let's look at what the experts have to say: can you take Unisom while pregnant?

The image of the glowing mama-to-be in all her tranquil glory is everywhere.

But sometimes it's just not like that. Sometimes that glow is just perspiration from throwing up.

Yep, pregnancy can be tough, especially if you are struggling with pregnancy-induced insomnia and nausea.

It's natural to want some relief from pregnancy symptoms, and Unisom may seem like the perfect candidate.

The question is, can you take Unisom while pregnant?

Is it safe?

And if so, how much can you have?

Let’s dive in.

In this article: 📝

What is Unisom?

Unisom is the brand name for an antihistamine called doxylamine, used to treat sleeplessness and, as we’ll find out, pregnancy nausea.

(Psst. We’re not even going to mention “morning sickness.” Check out our #RenamingRevolution to find out why.)

When doxylamine (Unisom) is combined with vitamin B6, it is sold under the brand name Diclegis as a prescription medication specifically for nausea and vomiting in pregnancy.

This may sound like music to your ears if you’re struggling with these symptoms.

Severe nausea and lack of sleep can be absolutely debilitating.

In its worst form, pregnancy nausea is called Hyperemesis Gravidarum.

It can cause weight loss and dehydration and really takes its toll on your body and emotional state.

It deserves and needs specialized care and is not something you just have to cope with.

That’s why it’s important to check in with your doctor and talk through the benefits and risks of treatment.

You don't have to suffer in silence.

Can Unisom hurt my unborn baby?

Top of your mind is no doubt, is Unisom safe for you and your baby?

There’s good news here.

There are many studies suggesting that antihistamines like doxylamine (Unisom’s active ingredient) are likely safe for use in pregnancy.

And Diclegis (doxylamine + vitamin B) has been approved by the FDA for use in pregnant women.

The American College of Obstetricians and Gynecologists (ACOG) suggests that if lifestyle and diet changes don't help with nausea, you should try vitamin B6 supplements next.

If this doesn’t help, you can combine vitamin B6 with doxylamine.

You can do this by taking them separately or by trying the prescription medication Diclegis which blends the two.

Is Unisom safe during the first trimester?

The first trimester is such a delicate time.

You’re nervous, excited, and maybe rather nauseous.

In these early weeks, your baby is growing and developing rapidly—and the most sensitive to certain factors that can cause birth differences.

Luckily, Unisom during pregnancy is not known to cause birth differences and is generally considered safe to use at all stages of pregnancy.

How many mg of Unisom is safe during pregnancy?

Unisom’s guidelines for adults are to take one 25mg tablet 30 min before bedtime or as directed by a doctor.

And that last part is really important. It’s always important to check in with your primary care provider before starting any medication while you’re pregnant.

This is partly to ensure that it does not interact negatively with any other medication you might be taking.

And partly so that they can monitor your symptoms to see that they do not signal that anything else is up.

Is it ok to take Unisom every night?

Apart from nausea, Unisom also works like a charm against those sleepless nights.

But is it safe to take Unisom every night?

Turns out, no, not really.

Unisom is recommended for occasional sleeplessness, rather than as an everyday medication.

If you’re experiencing sleeplessness for more than two weeks, it’s time to make that call to the doctor’s to discuss it.

What else can I take for sleeplessness while pregnant?

If you decide not to use Unisom, there are other things to try that may help you get to sleep.

One option is a pregnancy pillow which can help you find a comfortable sleeping position.

If you're on the hunt for the perfect pregnancy pillow, our Peanut moms-to-be love this one by Sleepybelly, which is totally adjustable, supports your bump, back, and hips, and comes highly recommended by doulas and midwives.

All the usual suspects can also help, like light exercise, not using your phone an hour before bed, and sleeping in a cool dark room.

Your doctor may also recommend a magnesium supplement.

Or, if your lack of z’s is due to restless legs syndrome, they may suggest you up your iron intake.

We know. It’s a lot.

This, too, shall pass.

And just because these symptoms are common, it doesn't mean you shouldn’t ask for help.

Speak to your doctor or midwife about safe options to find relief.

Lean on your people for help with your daily duties.

And don't forget your Peanut Community — they'll be there for you, 24/7, whenever you need someone to talk to.

We’re in this together.