Feeling exhausted on Oestradiol

Hello everyone,

This is my fourth IVF round, and second FET. This time I’m on a high dose of Oestradiol (Progynova) - 2 tablets 3 times per day, plus one tablet twice a day taken vaginally, and patches. And I’m EXHAUSTED! Tired when I wake up, and wanting to go to bed by 3pm! I didn’t experience this on the other rounds, and wondered if this is normal? Or am I coming down with something? I’m currently on day 19, and have been feeling like this for about a week, maybe a little less. I started progesterone today, ahead of the transfer on Tuesday.

What do you think?

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I’m on a similarly high dose and have felt exhausted, achy and had headaches. I’m on 4 tablets a day, and 50mg patches, plus cyclogest.
It does get better once your body gets used to it!
Fingers crossed for your FET! X

Both estrogen and progesterone will make you feel wiped. Just go easy on yourself - nap if you need to (but try not to fuck up your sleep cycle) and get your partner to pick up the slack around the house. Your body is doing important work right now, so treat it with kindness.

Thank you both, that’s really good to know! I was wondering if I’m maybe getting sick, which would not be ideal with a transfer on Tuesday! It’s just so strange that I felt nothing last time, but I’m dose is a lot higher this time.

I’m on 3 tablets twice a day and feel your pain. Feeling nauseous and getting horrible headaches. First time taking this medication- 2 failed fresh and one failed FET, trying to extra oestrogen and testosterone to see if this one will stick

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