Hi everyone, I've had a consultation with my current IVF doctor after three failed blastocyst transfers. I have no structural issues so my doctor suggested an emperical route which is to go on prednisolone and vaginal probiotics (I think Gynaflor?)..this is without doing any tests but from I understand both would help with microbiome and immunological issues respectively. Is this worth trying or should I go away and do my own immunology tests (my clinic doesnt do them so I have to find my own one) and the microbiome test? My doctor said that if they found anything, I would be put on the treatment she is suggesting anyway. But I'm guessing the tests could reveal more that could lead to a more personalised treatment plan. Really confused about what to do and obviously don't want to put myself through more endless tests for little gain!
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I was on prednisone as part of an immune protocol but not the other drug you mentioned. My personal RI also included a higher dose of progesterone, palquenil and tacrolimus as part of my protocol. Dosing changed throughout my pregnancy.
With that being said I think it'd up to you to give it another go with this change before seeking out an RI and possibly more meds and testing. I think time (such as travel to an RI) and cost should be considered too. Also, age could be a factor too depending on your situation.
I am optimistic to hear atleast your RE is attempting something new rather than the same failing protocol over and over. However if I reached a dead end with my RE or they wanted to repeat failing ideas, I'd personally go to an RI.