Letrozole

Has anyone ever conceived on first cycle of letrozole? Just out of curiosity 😊

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Hi Jess, I hope it’s ok to ask, but where are you having letrozole? I’ve heard such good things but I’ve been under two clinics that don’t prescribe it, only gonal-f or menopuer xx

Hey. Course. I’m having mine through the clinic x

Yeah which one? Dr Reddy in Cheltenham?

I am on cycle 7 :(

do you have just that or a combination? At Cheltenham? I’m on menopuer with ovulation induction but they don’t do it in Cheltenham.

Yer started on clomid to regulate my periods and now just on letrozole

I’m wondering if it’s a drug associated with PCOS etc?

I did three cycles and did not ovulate either time each dose progressively getting higher. After that my clinic put me on Metformin and myoinositols and I got pregnant Within that cycle.

ah yes, metformin has a good reputation for people with certain needs. I have a couple of pals who really champion it. I haven’t heard of the other drug but PCOS related I think.

I don’t have PCOS but I read that letrozole mixed with fsh drugs are useful for older ladies (I’m 43) but haven’t heard of it until recently and thought it was an overseas thing x

yes thats the one 😁

ah awesome. I’m seeing after my period this month so we’ll ask her about it. She had clear views on the drugs I was given at another clinic so I’m trying to learn about things!

oh bless you, fingers crossed! This is my first cycle in a year, so just regulating that x

ahh ok! Good to know, just interesting to see what works for people and wasnt doesn’t x

yeah she’s brilliant, I do really like her 😊

I have PCOS and tried for years to conceive and started Letrozole and conceived first time! Now have a 6 week old! Works so different for everyone I have noticed! So hopefully first time for you too!

congratulations Lauren, what was your protocol? I’m really interested to try it ☺️

I was referred to the assisted conception unit due to my pcos and not ovulating. I was given a choice of Letrozole or Clomid. Ended up doing a bit of research myself and most studies showed more likelihood of pregnancy, healthier pregnancies and higher live birth numbers with Letrozole over clomid so chose Letrozole!
Got prescribed the Letrozole along with a medication that would start my period as they were irregular. Didn’t end up using the other medication though as period came naturally that month. Was started on 5mg of Letrozole although I think the usual starting does is 2.5mg so unsure why I was started on 5mg. You take the Letrozole on the second day of your period for 5 days straight. So days 2-6 of your cycle. At around day 10 I got a scan on my ovaries to see if there was a dominant follicle and if it was likely I would ovulate. They look at the lining of your uterus to see if it has thickened enough and the size of your follicle with an internal scan.

Ran out of space sorry for the essay! Haha.
If you have multiple dominant follicles they don’t want you to have sex as the risk of multiples is high. So I was told I was likely to ovulate so then I went for a blood test on day 20 to check progesterone levels which if they are high enough show that you ovulated. If you do you just wait to take a pregnancy test and they said if you don’t they will increase the dose of Letrozole after 3 months at the same does I believe it was! Not 100% sure on that though! So ultimately you take the pills day 2-6 have a scan and a blood test within the cycle!
Then if you do get pregnant you get an early scan at 7 weeks to check where pregnancy is and if it is developing well!

Sorry for how long that was. Hope that’s the info you wanted! Sorry if I’ve just waffled for no reason 🤣🤣

I have PCOS and it took me 3 cycles of letrazole to conceive, currently 32 weeks pregnant, clomid didn't work for me at all x

you are a superstar! This is brilliant information! I’m on FSH/LH stimulation and growing two follicles on that they’ve pushed to reach maturity and then triggered ovulation for timed intercourse. I’m wondering if letrozole will stimulate more follicles and therefore allow us to try ivf with more success. They don’t feel it’s quiet my while with just two so it’s worth asking about and you’ve really helped me to have an educated conversation. Do you know how much a treatment cycle is? The drug I’m on is so expensive.
I think they also mix gonal-f with letrozole which is useful in older patients like me apparently! Xxx

in our community

Love my husband. Love my kids. But…

I’m 32 weeks pregnant with twins. I take care of my 4 yo, 2 yo, and 1 yo. I barely have energy to stand anymore. I cuddle and watch movies with my kids all day at this point. My husband is less pushy in this pregnancy in wanting to be touched or love up on me. But I feel more like a tool these days more than ever. He gets frustrated (not to a crazy degree) but I can tell he huffs because he’s probably sexually frustrated from me not wanting to be touched on. (my boobs are super sensitive atm) I love having the babies part, but the pregnancy also now has me feeling like a baby making machine. And a tool with big boobs made for touches and my husbands pleasure. Ofc I love my husband and kids, but with my hormones all wack, it really doesn’t feel the same when you’re not turned on. It’s so hard for me to get turned on. I’m uncomfortable all the time in my own body. Babies moving in there all the time. My children cuddle me all day but get rowdy at the end of the day, so I end up getting touched out and I can get irritable when my husband tries to touch me affectionately. He doesn’t have the tact necessary for me right now, when I wish he wanted to go in for a normal comforting hug I’m let down more often than not, there is almost always a boob groping involved as well. I tried to just let him touch me last night so he could get it out of his system, but he could tell I felt tense. Wish my boobs weren’t such an uncomfortable place for me to be touched. Idk why I’m making this post. Probably just to vent. Wish men were equally as emotionally intelligent as women. Wish I didn’t feel like I still owe him something because he’s picking up a lot of the house load and yet I still need to ask him to do more before these twins arrive. He’s tired every day when he comes home, so he takes a shower sometimes works out, and helps get the kids to bed. So it’s a struggle getting him to help any further than that. Weekends are my only time to get to him. But it’s a struggle to find time on weekends too. I know if he wanted to he would. But there’s just no drive.

Go to dinner ideas

Looking for recipes you use in your family that are not the traditional lasagna, shepards pie, ect

If you DO NOT buy things second hand, it is mainly because:

Answer only if it applies to you.

What are we giving our soon-to-be 3yo for their birthdays?

We have the magnetiles, we have the kinetic sand and play doh, we have the play kitchen…

Literally, is there anything left in the world to buy this spoilt kid? 😅

Baby groups?

Hello there!!
I hope you enjoying the 5month babies 🫠 the cuteness outweighs everything over here.
We live in the area of Croydon & need to start going to baby groups ( I NEED it more than him though) but I am a little bit clueless. Any recommendations?
We are happy to travel a bit too.
Thanks ☺️

Hiiii!

Hey yall! I’m Mahala and socially awkward as hell. I’m looking for other moms to connect with to hang out in person or on FaceTime. Drink coffee while the kids destroy the house. Literally anything. Making friends is hard in motherhood when you don’t know how to talk to people. I’m pretty low maintenance friend and we can talk whenever. And I’m down to do anything within reason. Let’s chat!